Biological Sciences Program

The Biological Sciences (BS) Program is designed for researchers and professionals with interests in the biological processes that underlie aging. Symposia and poster sessions will address the aging process at the molecular, cellular, and organismal level, as well as the specific disease conditions that are related to, or that accompany, the aging process.  Organized by the GSA Biological Sciences Section.

Biological Sciences Minority Investigator Travel Awards
Minority Investigator Travel Awards for students and post docs are available to support attendance at the 2019 Annual Scientific Meeting by individuals from groups underrepresented in biomedical research. This year, the Biological Sciences Section will award up to 8 travel awards in the amount of $1000 each for qualified attendees.

To be considered for the travel award, you must answer YES to the following question on the authors task of the abstract submission, “Is the author an individual from an underrepresented population in the biomedical, clinical, behavioral and social science as defined by the National Institutes of Health, Diversity in Extramural Programs.” Abstract submissions are due March 14. 
Experience five days of learning and training that include:

2019 Biological Sciences Program 

Wednesday, November 13

8 a.m. to 12:00 p.m. • No Fee (Separate Registration Required)
Pre-Conference Workshop
One Health for Healthy Aging: How Companion Animals Can Help Us Solve Aging
Speakers: Kate Creevy, Texas A&M University; Silvan Urfer, University of Washington; Natasha Olby, NC State; Daria Fleyshman Vaika; Daniel Promislow, University of Washington
Companion dogs age much like we do, but they do so at an accelerated rate. The "One Health for Healthy Aging" pre-conference workshop will explore how companion dogs are informing us about mechanisms of biological aging and potential interventions to delay age-related declines in function and disease.
Supported by the University of Washington Nathan Shock Center.

12:30 to 2:00 p.m.
Expanding the Network: Non-Traditional Organismal Models in Geroscience

  • Conservation of Integrative Physiological Aging Mechanisms Across Primates, Alan Cohen
  • Mechanisms of Longevity: Lessons from Long-Lived Mammals, Vera Gorbunova
  • Genome-Wide Relaxation of Selective Contraints Underlies the Evolution of Short Life Span in African Killifishes, Dario Riccardo Valenzano 
  • Marmoset Monkeys as a Model of Aging, Suzette Tardif

2:30 to 4:00 p.m.
DNA Methylation: Cause or Consequence of Aging?

  • A Functional Epigenetic Clock for Rats, Morgan Levine
  • Longitudinal Trajectories of Epigenetic Clocks in Humans and Effects of Medication Use, Sara Haag
  • Epigenetic Predictors of Lifespan and Health Span, Ake Lu
  • Robust Biomarkers of Aging and Their Biological Origin, Dimitriy Podoloskiy

4:30 to 6:00 p.m.
Probing the Complex Interactions Between Diet, Disease, and Aging

  • Extending Healthspan and Lifespan: Insghts from Nutritional Geometry, Samantha Solon-Biet
  • Novel Methionine-Related Interventions that Confer Healthspan Benefits to Yeast and Rodents, Jay Johnson
  • Metabolic Integrity - A Factor in Aging an a Player in the Mechanisms of CR, Rozalyn Anderson

6:00 to 8:00 p.m.
President's Welcome Reception and Exhibit Hall Opening
BS Poster Session (Face-to-Face Time with Presenters 6 to 7 pm)

Thursday, November 14

8:00 to 9:30 a.m.
Systems Biology of Aging

  • Systems Level Understanding of Aging, Vyacheslav Labunsky
  • How Many Molecular Mechanisms Must be Altered Simultaneously to Slow Aging and Extend Lifespan, Nicholas Stroustrup
  • Waddington's landscape of Cell Aging, Nan Hou
  • A Screen of Wild-Derived Fly Strains reveals CG34351 as a Regulator Toxic Effects of a Rich Diet, Rachel Brem

10:00  to 11:30 a.m.
President’s Opening Plenary Session

12:00 to 1:30 p.m.
Biological Sciences Presidential Symposium: Expanding the Geroscience Network
Matt Kaeberlein

  • Omics in Aging Research: From Biomarkers to Systems Biology, Daniel Promislow
  • Heterogeneity of Aging in Human Populations, Jing-dong (Jackie) Han
  • Epigenetic and metabolic regulation of aging, Anne Brunet

1:30 to 3:30 p.m.
Poster Session II

5:00 to 6:30 p.m. 
Targeting the mTOR Network to Maximize Healthspan

  • Mechanisms of Neuroprotection by mTOR Inhibitors, Veronica Galvan
  • Sex and Tissue Specific Roles of mTORC2 in Healthspan, Metabolism and Survival, Dudley Lamming
  • Anti-Cell Senescent Effects of Rapamycin and Their Role in Diseases, Including Alzheimer's, Viviana Perez

Friday, November 15

8:00 to 9:30 a.m.
Is Aging an Acquired Mitochondrial Disease?

  • Turning the Oxygen Dial as a Therapy: Hypoxia Treatment for Mitochondrial Dysfunction, Isha Jain
  • Aging and Mitochondrial Disease: Shared Mechanisms and Therapies?, Alessandro Bitto
  • Mitochondria as Reversible Regulators of Aging Associated Skin Wrinkles and Hair Loss in Mice, Keshav Singh

10:00 to 11:30 a.m.
ESPO/ Biological Sciences Section Symposium: The Crossroads of Aging—Targeting Immunity, Metabolism, and Cellular Stress
Matt Kaeberlein, Jessica Hoffman

12:00 to 1:30 p.m.
BS Section Business Meeting and Award Presentation
separate registration required

5:00 to 8:00 p.m.
Irving S. Wright and Vincent Cristofalo “Rising Star” Award Presentation, Lecture, and Reception

These awards are given by American Federation for Aging Research (AFAR) Inc.

Saturday, November 16

8:00 to 9:30 a.m.
Mechanisms of Cognitive and Neurological Aging

  • Mechanisms of Brain Rejuvenation, Saul Villeda
  • Jump Around Jump Around: Transposable Element Activation in Neurodegenerative Taupathy, Bess Frost
  • Multi-Omics Analysis Identifies Gene Networks Associated With Cognitive Aging and Alzheimer's Disease, Catherine Kaczorowski

10:00 to 10:30 a.m.
GSA Business Meeting and Installtion of 2020 GSA President

10:30 to 11:45 a.m.
Kent and Kleemeier Award Lectures and Installation of 2020 GSA President

12:00 to 1:30 pm
Intervening in the Longevity Network

  • Targeting Tryptophan-Kynurenine Metabolism to Extend Lifespan and Treat Age-Associated Disease, George Sutphin
  • Increased Lifespan Through Altered Gcn4/ ATF-5 in S. Cerevisiae and C. Elegans, Mark McCormick
  • Leveraging Drug-Drug Interactions for Pharmacological Extension of Healthy Lifespan, Jan Gruber
  • Understanding Aging in Terms of Physiological States, Alex Mendenhall

3:30 to 5:00 p.m.
Cell Non-Autonomous Mechanisms of Aging

  • Cell Non-Autonomous Serotonin Signaling Mediates Stress Resistance and Longevity, Scott Leiser
  • Neuronal FGF-21 Signaling: A Sensor of Dietary Protein, Cristal Hill
  • Increase in HSP25 Extends Lifespan and Improves Response to Tau Toxcitiy Through a Call, Non-Autonomous Mechanism, Karl Rodriguez

5:30 to 7:00 p.m.
Immunity and Aging - The Human Face

  • Dynamics of Human Mucosal-Associated Invariant T Cell Repertoires Across the Human Life-Span, Liyen Loh
  • Aged Induces an Emergence From Melanoma Dormancy, Mitchell Fane
  • Sex-Dimorphism in the Genomic Regulation of Aging, Berenice Benayoun

Sunday, November 18

9:00 to 11:30 a.m.
Clinical Trials in Geroscience

  • Cellular Senecence as a Therapeutic Target for Geroscience-Guided Clinical Trials, Jamie Justice
  • TORC1 Inhibition as an Immunotherapy to Decrease Infections in the Elderly, Joan Mannick


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